Zonulin and claudin-5 levels in multisystem inflammatory syndrome and SARS-CoV-2 infection in children.

Ahmet Osman Kılıç Fatih AkınAbdullah YazarÖzge Metin AkcanCemile TopcuOrkun Aydın

Published in: Journal of paediatrics and child health (2022)

These results indicate that increased intestinal permeability may be involved in the pathogenesis of SARS-CoV-2 infection and MIS-C disease. Larger clinical trials are needed to clarify the role of serum zonulin and claudin-5 on intestinal permeability in MIS-C and SARS-CoV-2 infection in children.

Keyphrases

clinical trial
respiratory syndrome coronavirus
young adults
endothelial cells
oxidative stress
sars cov
randomized controlled trial
case report
phase ii
open label