An Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients.

Nicole G ChauClement MaKristina DangaHasan Al-SayeghValentina NardiRyan BarretteChristopher S LathanSteven G DuBoisRobert I HaddadGeoffrey I Shapiro Stephen E Sallan Arindam DharJeanenne J NelsonChristopher A French

Published in: JNCI cancer spectrum (2019)

We identify three risk groups defined by anatomic site and NUT fusion type. Nonthoracic primary with non-BRD4-NUT fusion confers the best prognosis, followed by nonthoracic primary with BRD4-NUT. Thoracic NC patients, regardless of the NUT fusion, have the worst survival.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
spinal cord
prognostic factors
gene expression
dna methylation
copy number
amino acid
patient reported outcomes