Geoffrey I Shapiro (Geoffrey Shapiro)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 84

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

JCO precision oncology

Nature communications

Molecular cancer therapeutics

Dana Farber Cancer Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Dana Farber Cancer Institute Jul 01 1991

United States

Director, Early Drug Development Center :: Department of Medical Oncology

Publications

Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, null null, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics 23 (7) (2024)
Alexandre Andre Balieiro Anastacio da Costa, Ozge Somuncu, Ramya Ravindranathan, Sirisha Mukkavalli, David B Martignetti, Huy Nguyen, Yuqing Jiao, Benjamin P Lamarre, Golbahar Sadatrezaei, Lisa A Moreau, Joyce F Liu, Divya Ramalingam Iyer, Jean-Bernard Lazaro, Geoffrey I Shapiro, Kalindi Parmar, Alan D' Andrea
Single-stranded DNA Gap Accumulation is a Functional Biomarker for USP1 Inhibitor Sensitivity. Cancer research (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics (2024)
Edward B Maldonado, W Kimryn Rathmell, Geoffrey I Shapiro, Naoko Takebe, Jordi Rodon Ahnert, Devalingam Mahalingam, Nikolaos A Trikalinos, Arash Rezazadeh Kalebasty, Mamta Parikh, Scott A Boerner, Celene Balido, Gregor Krings, Timothy F Burns, Emily K Bergsland, Pamela N Munster, Alan Ashworth, Patricia M LoRusso, Rahul R Aggarwal
A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170). Cancer research communications 4 (7) (2024)
Panagiotis A Konstantinopoulos, Su-Chun Cheng, Elizabeth K Lee, Alexandre Andre Balieiro Anastacio da Costa, Doga C Gulhan, Andrea E Wahner Hendrickson, Bose S Kochupurakkal, David L Kolin, Elise C Kohn, Joyce F Liu, Richard T Penson, Elizabeth H Stover, Jennifer Curtis, Hannah Sawyer, Madeline Polak, Dipanjan Chowdhury, Alan D' Andrea, Anniina Färkkilä, Geoffrey I Shapiro, Ursula A Matulonis
Randomized Phase II Study of Gemcitabine With or Without ATR Inhibitor Berzosertib in Platinum-Resistant Ovarian Cancer: Final Overall Survival and Biomarker Analyses. JCO precision oncology 8 (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Edward B Maldonado, W Kimryn Rathmell, Geoffrey I Shapiro, Naoko Takebe, Jordi Rodon Ahnert, Devalingam Mahalingam, Nikolaos A Trikalinos, Arash Rezazadeh Kalebasty, Mamta Parikh, Scott A Boerner, Celene Balido, Gregor Krings, Timothy F Burns, Emily K Bergsland, Pamela N Munster, Alan Ashworth, Patricia M LoRusso, Rahul R Aggarwal
A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170). Cancer research communications 4 (7) (2024)
Panagiotis A Konstantinopoulos, Su-Chun Cheng, Elizabeth K Lee, Alexandre Andre Balieiro Anastacio da Costa, Doga C Gulhan, Andrea E Wahner Hendrickson, Bose S Kochupurakkal, David L Kolin, Elise C Kohn, Joyce F Liu, Richard T Penson, Elizabeth H Stover, Jennifer Curtis, Hannah Sawyer, Madeline Polak, Dipanjan Chowdhury, Alan D' Andrea, Anniina Färkkilä, Geoffrey I Shapiro, Ursula A Matulonis
Randomized Phase II Study of Gemcitabine With or Without ATR Inhibitor Berzosertib in Platinum-Resistant Ovarian Cancer: Final Overall Survival and Biomarker Analyses. JCO precision oncology 8 (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics (2024)
Ryan B Corcoran, Khanh T Do, Jeong Eun Kim, James M Cleary, Aparna Raj Parikh, Oladapo O Yeku, Niya Xiong, Colin D Weekes, Jennifer T Veneris, Leanne G Ahronian, Gianluca Mauri, Jun Tian, Bryanna L Norden, Alexa G Michel, Emily E Van Seventer, Giulia Siravegna, Kyle Camphausen, Gary Chi, Isobel J Fetter, Joan S Brugge, Helen X Chen, Naoko Takebe, Richard T Penson, Dejan Juric, Keith T Flaherty, Ryan J Sullivan, Jeffrey W Clark, Rebecca S Heist, Ursula A Matulonis, Joyce F Liu, Geoffrey I Shapiro
Phase I/II Study of Combined BCL-xL and MEK Inhibition with Navitoclax and Trametinib in KRAS or NRAS Mutant Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, null null, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics 23 (7) (2024)
Alexandre Andre Balieiro Anastacio da Costa, Ozge Somuncu, Ramya Ravindranathan, Sirisha Mukkavalli, David B Martignetti, Huy Nguyen, Yuqing Jiao, Benjamin P Lamarre, Golbahar Sadatrezaei, Lisa A Moreau, Joyce F Liu, Divya Ramalingam Iyer, Jean-Bernard Lazaro, Geoffrey I Shapiro, Kalindi Parmar, Alan D' Andrea
Single-stranded DNA Gap Accumulation is a Functional Biomarker for USP1 Inhibitor Sensitivity. Cancer research (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics (2024)
Edward B Maldonado, W Kimryn Rathmell, Geoffrey I Shapiro, Naoko Takebe, Jordi Rodon Ahnert, Devalingam Mahalingam, Nikolaos A Trikalinos, Arash Rezazadeh Kalebasty, Mamta Parikh, Scott A Boerner, Celene Balido, Gregor Krings, Timothy F Burns, Emily K Bergsland, Pamela N Munster, Alan Ashworth, Patricia M LoRusso, Rahul R Aggarwal
A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170). Cancer research communications 4 (7) (2024)
Ryan B Corcoran, Khanh T Do, Jeong Eun Kim, James M Cleary, Aparna Raj Parikh, Oladapo O Yeku, Niya Xiong, Colin D Weekes, Jennifer T Veneris, Leanne G Ahronian, Gianluca Mauri, Jun Tian, Bryanna L Norden, Alexa G Michel, Emily E Van Seventer, Giulia Siravegna, Kyle Camphausen, Gary Chi, Isobel J Fetter, Joan S Brugge, Helen X Chen, Naoko Takebe, Richard T Penson, Dejan Juric, Keith T Flaherty, Ryan J Sullivan, Jeffrey W Clark, Rebecca S Heist, Ursula A Matulonis, Joyce F Liu, Geoffrey I Shapiro
Phase 1/2 study of combined BCL-xL and MEK inhibition with navitoclax and trametinib in KRAS or NRAS mutant advanced solid tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Edward B Maldonado, W Kimryn Rathmell, Geoffrey I Shapiro, Naoko Takebe, Jordi Rodon Ahnert, Devalingam Mahalingam, Nikolaos A Trikalinos, Arash Rezazadeh Kalebasty, Mamta Parikh, Scott A Boerner, Celene Balido, Gregor Krings, Timothy F Burns, Emily K Bergsland, Pamela N Munster, Alan Ashworth, Patricia M LoRusso, Rahul R Aggarwal
A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170). Cancer research communications (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, null null, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics 23 (7) (2024)
Ryan B Corcoran, Khanh T Do, Jeong Eun Kim, James M Cleary, Aparna Raj Parikh, Oladapo O Yeku, Niya Xiong, Colin D Weekes, Jennifer T Veneris, Leanne G Ahronian, Gianluca Mauri, Jun Tian, Bryanna L Norden, Alexa G Michel, Emily E Van Seventer, Giulia Siravegna, Kyle Camphausen, Gary Chi, Isobel J Fetter, Joan S Brugge, Helen X Chen, Naoko Takebe, Richard T Penson, Dejan Juric, Keith T Flaherty, Ryan J Sullivan, Jeffrey W Clark, Rebecca S Heist, Ursula A Matulonis, Joyce F Liu, Geoffrey I Shapiro
Phase I/II Study of Combined BCL-xL and MEK Inhibition with Navitoclax and Trametinib in KRAS or NRAS Mutant Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Ryan B Corcoran, Khanh T Do, Jeong Eun Kim, James M Cleary, Aparna Raj Parikh, Oladapo O Yeku, Niya Xiong, Colin D Weekes, Jennifer T Veneris, Leanne G Ahronian, Gianluca Mauri, Jun Tian, Bryanna L Norden, Alexa G Michel, Emily E Van Seventer, Giulia Siravegna, Kyle Camphausen, Gary Chi, Isobel J Fetter, Joan S Brugge, Helen X Chen, Naoko Takebe, Richard T Penson, Dejan Juric, Keith T Flaherty, Ryan J Sullivan, Jeffrey W Clark, Rebecca S Heist, Ursula A Matulonis, Joyce F Liu, Geoffrey I Shapiro
Phase I/II Study of Combined BCL-xL and MEK Inhibition with Navitoclax and Trametinib in KRAS or NRAS Mutant Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics (2024)
Ryan B Corcoran, Khanh T Do, Jeong Eun Kim, James M Cleary, Aparna Raj Parikh, Oladapo O Yeku, Niya Xiong, Colin D Weekes, Jennifer T Veneris, Leanne G Ahronian, Gianluca Mauri, Jun Tian, Bryanna L Norden, Alexa G Michel, Emily E Van Seventer, Giulia Siravegna, Kyle Camphausen, Gary Chi, Isobel J Fetter, Joan S Brugge, Helen X Chen, Naoko Takebe, Richard T Penson, Dejan Juric, Keith T Flaherty, Ryan J Sullivan, Jeffrey W Clark, Rebecca S Heist, Ursula A Matulonis, Joyce F Liu, Geoffrey I Shapiro
Phase I/II Study of Combined BCL-xL and MEK Inhibition with Navitoclax and Trametinib in KRAS or NRAS Mutant Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics (2024)
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa Meier McShane, Michael T Lewis, Kurt W Evans, Dali Li, Lawrence V Rubinstein, Alana L Welm, Dennis A Dean, Anuj Srivastava, Jeffrey W Grover, Min Jin Ha, Huiqin Chen, Xuelin Huang, Kaushik Varadarajan, Jing Wang, Jack A Roth, Bryan E Welm, Ramaswamy Govindan, Li Ding, Salma Kaochar, Nicholas Mitsiades, Luis G Carvajal Carmona, Meenhard Herylyn, Michael A Davies, Geoffrey I Shapiro, Ryan C Fields, Jose G Trevino, Joshua C Harrell, James H Doroshow, Jeffrey H Chuang, Jeffrey A Moscow
Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Molecular cancer therapeutics (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Panagiotis A Konstantinopoulos, Su-Chun Cheng, Elizabeth K Lee, Alexandre Andre Balieiro Anastacio da Costa, Doga C Gulhan, Andrea E Wahner Hendrickson, Bose S Kochupurakkal, David L Kolin, Elise C Kohn, Joyce F Liu, Richard T Penson, Elizabeth H Stover, Jennifer Curtis, Hannah Sawyer, Madeline Polak, Dipanjan Chowdhury, Alan D' Andrea, Anniina Färkkilä, Geoffrey I Shapiro, Ursula A Matulonis
Randomized Phase II Study of Gemcitabine With or Without ATR Inhibitor Berzosertib in Platinum-Resistant Ovarian Cancer: Final Overall Survival and Biomarker Analyses. JCO precision oncology 8 (2024)
Curigliano Giuseppe, Geoffrey I Shapiro, Rebecca S Kristeleit, Albiruni R Abdul Razak, Stephen Leong, Maria Alsina, Antonio Giordano, Karen A Gelmon, Erica Stringer-Reasor, Ulka N Vaishampayan, Mark Ross Middleton, Anthony J Olszanski, Hope S Rugo, Kenneth A Kern, Nuzhat Pathan, Rachelle Perea, Kristen J Pierce, Sarah C Mutka, Zev A Wainberg
Correction to: A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer. British journal of cancer (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Brandon M Huffman, Hanrong Feng, Kalindi Parmar, Junning Wang, Kevin S Kapner, Bose S Kochupurakkal, David B Martignetti, Golbahar Sadatrezaei, Thomas A Abrams, Leah H Biller, Marios Giannakis, Kimmie Ng, Anuj K Patel, Kimberley J Perez, Harshabad Singh, Douglas A Rubinson, Benjamin L Schlechter, Elizabeth Andrews, Alison M Hannigan, Stanley Dunwell, Zoe Getchell, Srivatsan Raghavan, Brian M Wolpin, Caroline Fortier, Alan D' Andrea, Andrew J Aguirre, Geoffrey I Shapiro, James M Cleary
A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
James J Harding, Sarina A Piha-Paul, Ronak H Shah, Jessica J Murphy, James M Cleary, Geoffrey I Shapiro, David I Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M Ford, Mónica Arnedos, Salomon M Stemmer, Christelle De La Fouchardière, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S Duygu Selcuklu, Michael F Berger, Lisa D Eli, Funda Meric-Bernstam, Komal Jhaveri, David B Solit, Ghassan K Abou-Alfa
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers. Nature communications 14 (1) (2023)
Funda Meric-Bernstam, James M Ford, Peter J O'Dwyer, Geoffrey I Shapiro, Lisa Meier McShane, Boris Freidlin, Roisin E O'Cearbhaill, Suzanne George, Julia L Glade Bender, Gary H Lyman, James V Tricoli, David R Patton, Stanley R Hamilton, Robert C Gray, Douglas S Hawkins, Bhanumati Ramineni, Keith T Flaherty, Petros D Grivas, Timothy Anthony Yap, Jordan D Berlin, James H Doroshow, Lyndsay N Harris, Jeffrey A Moscow
National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D' Andrea, Geoffrey I Shapiro
Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer. Nature communications 14 (1) (2023)
Rachel B Keller, Tali Mazor, Lynette M Sholl, Andrew J Aguirre, Harshabad Singh, Nilay S Sethi, Adam Bass, Ankur K Nagaraja, Lauren K Brais, Emma Hill, Connor J Hennessey, Margaret Cusick, Catherine Del Vecchio Fitz, Zachary Zwiesler, Ethan Siegel, Andrea Ovalle, Pavel Trukhanov, Jason Hansel, Geoffrey I Shapiro, Thomas A Abrams, Leah H Biller, Jennifer A Chan, James M Cleary, Steven M Corsello, Andrea C Enzinger, Peter C Enzinger, Robert J Mayer, Nadine Jackson McCleary, Jeffrey A Meyerhardt, Kimmie Ng, Anuj K Patel, Kimberley J Perez, Osama E Rahma, Douglas A Rubinson, Jeffrey S Wisch, Matthew B Yurgelun, Michael J Hassett, Laura Macconaill, Deborah Schrag, Ethan Cerami, Brian M Wolpin, Jonathan Andrew Nowak, Marios Giannakis
Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer. JCO precision oncology 7 (2023)
James J Harding, Sarina A Piha-Paul, Ronak H Shah, Jessica J Murphy, James M Cleary, Geoffrey I Shapiro, David I Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M Ford, Mónica Arnedos, Salomon M Stemmer, Christelle De La Fouchardière, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S Duygu Selcuklu, Michael F Berger, Lisa D Eli, Funda Meric-Bernstam, Komal Jhaveri, David B Solit, Ghassan K Abou-Alfa
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers. Nature communications 14 (1) (2023)
David S Hong, Michael A Postow, Bartosz Chmielowski, Ryan J Sullivan, Amita Patnaik, Ezra E W Cohen, Geoffrey I Shapiro, Conor E Steuer, Martin Gutierrez, Heather Yeckes-Rodin, Robert Ilaria, Brenda C O'Connell, Joanna Peng, Guangbin Peng, Nora Zizlsperger, Anthony W Tolcher, Jedd D Wolchok
Eganelisib, a First-in-Class PI3K-γ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Michael L Cheng, Yeying Huang, Nhi Luong, Jaclyn LoPiccolo, Mizuki Nishino, Lynette M Sholl, Lucian R Chirieac, Alison D Santucci, Michael S Rabin, Pasi A Janne, Shodeinde Coker, Jennifer R Diamond, John Hilton, Geoffrey I Shapiro, Christopher A French
Exceptional Response to Bromodomain and Extraterminal Domain Inhibitor Therapy With BMS-986158 in BRD4-NUTM1 NUT Carcinoma Harboring a BRD4 Splice Site Mutation. JCO precision oncology 7 (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Yeying Huang, R Taylor Durall, Nhi M Luong, Hans J Hertzler, Julianna Huang, Prafulla C Gokhale, Brittaney A Leeper, Nicole S Persky, David E Root, Praju Vikas Anekal, Paula Montero Llopis, Clement N David, Jeffery L Kutok, Alejandra Raimondi, Karan Saluja, Jia Luo, Cynthia A Zahnow, Biniam Adane, Kimberly Stegmaier, Catherine E Hawkins, Christopher Ponne, Quan Le, Geoffrey I Shapiro, Madeleine E Lemieux, Kyle P Eagen, Christopher A French
EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes. Cancer research (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Rachel B Keller, Tali Mazor, Lynette M Sholl, Andrew J Aguirre, Harshabad Singh, Nilay S Sethi, Adam Bass, Ankur K Nagaraja, Lauren K Brais, Emma Hill, Connor J Hennessey, Margaret Cusick, Catherine Del Vecchio Fitz, Zachary Zwiesler, Ethan Siegel, Andrea Ovalle, Pavel Trukhanov, Jason Hansel, Geoffrey I Shapiro, Thomas A Abrams, Leah H Biller, Jennifer A Chan, James M Cleary, Steven M Corsello, Andrea C Enzinger, Peter C Enzinger, Robert J Mayer, Nadine Jackson McCleary, Jeffrey A Meyerhardt, Kimmie Ng, Anuj K Patel, Kimberley J Perez, Osama E Rahma, Douglas A Rubinson, Jeffrey S Wisch, Matthew B Yurgelun, Michael J Hassett, Laura Macconaill, Deborah Schrag, Ethan Cerami, Brian M Wolpin, Jonathan Andrew Nowak, Marios Giannakis
Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer. JCO precision oncology 7 (2023)
Matthew A Ingham, Jacob B Allred, Li Chen, Biswasjit Das, Bose S Kochupurakkal, Katherine Gano, Suzanne George, Steven Attia, Melissa A Burgess, Mahesh Seetharam, Sosipatros A Boikos, Nam Q Bui, James L Chen, Julia L Close, Gregory M Cote, Premal H Thaker, Susan Percy Ivy, Sminu Bose, Alan D' Andrea, Adrian Mariño-Enriquez, Geoffrey I Shapiro, Gary K Schwartz
Phase II Study of Olaparib and Temozolomide for Advanced Uterine Leiomyosarcoma (NCI Protocol 10250). Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
R Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C Gokhale, Brittaney A Leeper, Joshua O Nash, Pedro L Ballester, Scott Davidson, Adam Shlien, Emmanuel Sotirakis, Fabien Bertaux, Vincent Dubus, Jia Luo, Catherine J Wu, Derin B Keskin, Kyle P Eagen, Geoffrey I Shapiro, Christopher A French
The BRD4-NUT fusion alone drives malignant transformation of NUT carcinoma. Cancer research (2023)
James J Harding, Sarina A Piha-Paul, Ronak H Shah, Jessica J Murphy, James M Cleary, Geoffrey I Shapiro, David I Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M Ford, Mónica Arnedos, Salomon M Stemmer, Christelle De La Fouchardière, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S Duygu Selcuklu, Michael F Berger, Lisa D Eli, Funda Meric-Bernstam, Komal Jhaveri, David B Solit, Ghassan K Abou-Alfa
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers. Nature communications 14 (1) (2023)
Funda Meric-Bernstam, James M Ford, Peter J O'Dwyer, Geoffrey I Shapiro, Lisa Meier McShane, Boris Freidlin, Roisin E O'Cearbhaill, Suzanne George, Julia L Glade Bender, Gary H Lyman, James V Tricoli, David R Patton, Stanley R Hamilton, Robert C Gray, Douglas S Hawkins, Bhanumati Ramineni, Keith T Flaherty, Petros D Grivas, Timothy Anthony Yap, Jordan D Berlin, James H Doroshow, Lyndsay N Harris, Jeffrey A Moscow
National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
James J Harding, Sarina A Piha-Paul, Ronak H Shah, Jessica J Murphy, James M Cleary, Geoffrey I Shapiro, David I Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M Ford, Mónica Arnedos, Salomon M Stemmer, Christelle De La Fouchardière, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S Duygu Selcuklu, Michael F Berger, Lisa D Eli, Funda Meric-Bernstam, Komal Jhaveri, David B Solit, Ghassan K Abou-Alfa
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers. Nature communications 14 (1) (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D' Andrea, Geoffrey I Shapiro
Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer. Nature communications 14 (1) (2023)
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D' Andrea, Geoffrey I Shapiro
Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer. Nature communications 14 (1) (2023)
Elizabeth Pan, Wanling Xie, Archana Ajmera, Arlene Araneta, Christina A M Jamieson, Edmund Folefac, Arif Hussain, Christos E Kyriakopoulos, Adam C Olson, Mamta Parikh, Rahul A Parikh, Biren Saraiya, Susan Percy Ivy, Eliezer Van Allen, Neal I Lindeman, Bose S Kochupurakkal, Geoffrey I Shapiro, Rana R McKay
A Phase I Study of Combination Olaparib and Radium-223 in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) with Bone Metastases (COMRADE). Molecular cancer therapeutics (2023)
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D' Andrea, Geoffrey I Shapiro
Retraction Note: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer. Nature communications 14 (1) (2023)
Jeffrey Patterson-Fortin, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K Mehta, Jennifer L Guerriero, Gerburg M Wulf, Brian M Wolpin, Ben Z Stanger, Andrew J Aguirre, James M Cleary, Alan D' Andrea, Geoffrey I Shapiro
Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer. Nature communications 14 (1) (2023)
Rachel B Keller, Tali Mazor, Lynette M Sholl, Andrew J Aguirre, Harshabad Singh, Nilay S Sethi, Adam Bass, Ankur K Nagaraja, Lauren K Brais, Emma Hill, Connor J Hennessey, Margaret Cusick, Catherine Del Vecchio Fitz, Zachary Zwiesler, Ethan Siegel, Andrea Ovalle, Pavel Trukhanov, Jason Hansel, Geoffrey I Shapiro, Thomas A Abrams, Leah H Biller, Jennifer A Chan, James M Cleary, Steven M Corsello, Andrea C Enzinger, Peter C Enzinger, Robert J Mayer, Nadine Jackson McCleary, Jeffrey A Meyerhardt, Kimmie Ng, Anuj K Patel, Kimberley J Perez, Osama E Rahma, Douglas A Rubinson, Jeffrey S Wisch, Matthew B Yurgelun, Michael J Hassett, Laura Macconaill, Deborah Schrag, Ethan Cerami, Brian M Wolpin, Jonathan Andrew Nowak, Marios Giannakis
Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer. JCO precision oncology 7 (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Biagio Ricciuti, Arielle Elkrief, Joao M Victor Alessi, Xinan Wang, Yvonne Y Li, Hersh V Gupta, Daniel M Muldoon, Arrien A Bertram, Federica Pecci, Giuseppe Lamberti, Alessandro Di Federico, Adriana P Barrichello, Victor R Vaz, Malini M Gandhi, Elinton Lee, Geoffrey I Shapiro, Hyesun Park, Mizuki Nishino, James R Lindsay, Kristen D Felt, Bijaya Sharma, Andrew D Cherniak, Scott J Rodig, Daniel R Gomez, Narek Shaverdian, Mehrdad Rakaee, Chaitanya Bandlamudi, Marc Ladanyi, Pasi A Janne, Adam J Schoenfeld, Lynette M Sholl, Mark M Awad, Michael L Cheng
Clinicopathologic, genomic, and immunophenotypic landscape of ATM mutations in non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Harshabad Singh, Rachel B Keller, Kevin S Kapner, Julien Dilly, Srivatsan Raghavan, Chen Yuan, Elizabeth F Cohen, Michael Yevgeniy Tolstorukov, Elizabeth Andrews, Lauren K Brais, Annacarolina F L Da Silva, Kimberley J Perez, Douglas A Rubinson, Rishi Surana, Marios Giannakis, Kimmie Ng, Thomas E Clancy, Matthew B Yurgelun, Benjamin L Schlechter, Jeffrey W Clark, Geoffrey I Shapiro, Michael H Rosenthal, Jason L Hornick, Valentina Nardi, Yvonne Y Li, Hersh V Gupta, Andrew D Cherniak, Matthew L Meyerson, James M Cleary, Jonathan Andrew Nowak, Brian M Wolpin, Andrew J Aguirre
Oncogenic drivers and therapeutic vulnerabilities in KRAS wild-type pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Curigliano Giuseppe, Geoffrey I Shapiro, Rebecca S Kristeleit, Albiruni R Abdul Razak, Stephen Leong, Maria Alsina, Antonio Giordano, Karen A Gelmon, Erica Stringer-Reasor, Ulka N Vaishampayan, Mark Ross Middleton, Anthony J Olszanski, Hope S Rugo, Kenneth A Kern, Nuzhat Pathan, Rachelle Perea, Kristen J Pierce, Sarah C Mutka, Zev A Wainberg
A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer. British journal of cancer (2022)
Felipe Batalini, Niya Xiong, Nabihah Tayob, Madeline Polak, Julia Eismann, Lewis C Cantley, Geoffrey I Shapiro, Viktor Adalsteinsson, Eric P Winer, Panagiotis A Konstantinopoulos, Alan D' Andrea, Elizabeth M Swisher, Ursula A Matulonis, Gerburg M Wulf, Erica L Mayer
Phase 1b Clinical Trial with Alpelisib plus Olaparib for Patients with Advanced Triple-Negative Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (8) (2022)
Melinda L Telli, Sara M Tolaney, Geoffrey I Shapiro, Mark Middleton, Simon R Lord, Hendrik Tobias Arkenau, Andrew N J Tutt, Vandana Abramson, Emma Dean, Tufia C Haddad, Robert Wesolowski, Jordi Ferrer-Playan, Thomas Goddemeier, Thomas Grombacher, Jennifer Dong, Patricia Fleuranceau-Morel, Ivan Diaz-Padilla, Ruth Plummer
Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer. NPJ breast cancer 8 (1) (2022)
Christopher A French, Michael L Cheng, Glenn J Hanna, Steven G DuBois, Nicole G Chau, Christine L Hann, Simone Storck, Ravi Salgia, Matteo Trucco, Jennifer Tseng, Anastasios Stathis, Richard L Piekarz, Ulrich M Lauer, Christophe Massard, Kelly Bennett, Shodeinde Coker, Ulrike Tontsch-Grunt, Martin L Sos, Sida Liao, Catherine J Wu, Kornelia Polyak, Sarina A Piha-Paul, Geoffrey I Shapiro
Report of the First International Symposium on NUT Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (12) (2022)
Constantia Pantelidou, Heta Jadhav, Aditi Kothari, Renyan Liu, Gerburg M Wulf, Jennifer L Guerriero, Geoffrey I Shapiro
STING agonism enhances anti-tumor immune responses and therapeutic efficacy of PARP inhibition in BRCA-associated breast cancer. NPJ breast cancer 8 (1) (2022)
Timothy Anthony Yap, Erika Paige Hamilton, Todd M Bauer, Ecaterina E Ileana Dumbrava, Rinath Jeselsohn, Aaron Enke, Sabrina Hurley, Kevin K Lin, Jenn Habeck, Heidi Giordano, Geoffrey I Shapiro
Phase Ib SEASTAR Study: Combining Rucaparib and Sacituzumab Govitecan in Patients With Cancer With or Without Mutations in Homologous Recombination Repair Genes. JCO precision oncology 6 (2022)
Nami Yamashita, Yoshihiro Morimoto, Atsushi Fushimi, Rehan Ahmad, Atrayee Bhattacharya, Tatsuaki Daimon, Naoki Haratake, Yuka Inoue, Satoshi Ishikawa, Masaaki Yamamoto, Tsuyoshi Hata, Sayuri Akiyoshi, Qiang Hu, Tao Liu, Henry G Withers, Song Liu, Geoffrey I Shapiro, Tomoharu Yoshizumi, Mark D Long, Donald W Kufe
MUC1-C Dictates PBRM1-Mediate Chronic Induction of Interferon Signaling, DNA Damage Resistance and Immunosuppression in Triple-Negative Breast Cancer. Molecular cancer research : MCR (2022)
Joseph Paul Eder, Deborah B Doroshow, Khanh T Do, Vicki L Keedy, Jeffrey S Sklar, Peter M Glazer, Ranjit Bindra, Geoffrey I Shapiro
Clinical Efficacy of Olaparib in IDH1/IDH2- Mutant Mesenchymal Sarcomas. JCO precision oncology 5 (2022)
Vivek Subbiah, Irene Brana, Alessandra Longhi, Valentina Boni, Jean-Pierre Delord, Ahmad Awada, Pascaline Boudou-Rouquette, John Sarantopoulos, Geoffrey I Shapiro, Anthony D Elias, Ravin Ratan, Cristian Fernandez, Carmen Kahatt, Martin Cullell-Young, Mariano Siguero, Ali Zeaiter, Sant P Chawla
Antitumor Activity of Lurbinectedin, a Selective Inhibitor of Oncogene Transcription, in Patients with Relapsed Ewing Sarcoma: Results of a Basket Phase II Study. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (13) (2022)
Atish D Choudhury, Celestia S Higano, Johann S de Bono, Natalie Cook, Dana E Rathkopf, Kari B Wisinski, Juan Martin-Liberal, Mark Linch, Elisabeth I Heath, Richard D Baird, Javier García Corbacho, Miguel Quintela-Fandino, Simon T Barry, Elza C de Bruin, Steve Colebrook, George Hawkins, Teresa Klinowska, Brijesh Maroj, Ganesh Moorthy, Peter G S Mortimer, Michele Moschetta, Myria Nikolaou, Liz Sainsbury, Geoffrey I Shapiro, Lillian L Siu, Aaron Richard Hansen
A Phase I Study Investigating AZD8186, a Potent and Selective Inhibitor of PI3Kβ/δ, in Patients with Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (11) (2022)
Joseph W Kim, Rana R McKay, Marc R Radke, Shilin Zhao, Mary-Ellen Taplin, Nancy B Davis, Paul Monk, Leonard J Appleman, Primo N Lara, Ulka N Vaishampayan, Jingsong Zhang, Asit K Paul, Glenn Bubley, Eliezer Van Allen, Serhan Ünlü, Ying Huang, Massimo Loda, Geoffrey I Shapiro, Peter M Glazer, Patricia M LoRusso, Susan Percy Ivy, Yu Shyr, Elizabeth M Swisher, Daniel P Petrylak
Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Jeffrey Patterson-Fortin, Arindam Bose, Wei-Chih Tsai, Carter Grochala, Huy Nguyen, Jia Zhou, Kalindi Parmar, Jean-Bernard Lazaro, Joyce F Liu, Kelsey McQueen, Geoffrey I Shapiro, David E Kozono, Alan D' Andrea
Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant Cancers. Cancer research 82 (20) (2022)
Sophie Cousin, Jean Yves Blay, Irene Braña Garcia, Johann S de Bono, Christophe Le Tourneau, Victor Moreno, Jose Trigo, Christine L Hann, Arun A Azad, Seock-Ah Im, Philippe A Cassier, Christopher A French, Antoine Italiano, Vicki L Keedy, Ruth Plummer, Marie-Paule Sablin, Matthew L Hemming, Geraldine Ferron-Brady, Anastasia Wyce, Ahmed Khaled, Antara Datta, Shawn W Foley, Michael T McCabe, Yuehui Wu, Thierry Horner, Brandon E Kremer, Arindam Dhar, Peter J O'Dwyer, Geoffrey I Shapiro, Sarina A Piha-Paul
Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein of the testis carcinoma and other cancers: Results of a Phase I/II open-label, dose escalation study. International journal of cancer (2021)
James M Cleary, Srivatsan Raghavan, Qibiao Wu, Yvonne Y Li, Liam F Spurr, Hersh V Gupta, Douglas A Rubinson, Isobel J Fetter, Jason L Hornick, Jonathan A Nowak, Giulia Siravegna, Lipika Goyal, Lei Shi, Lauren K Brais, Maureen Loftus, Atul B Shinagare, Thomas A Abrams, Thomas E Clancy, Jiping Wang, Anuj K Patel, Franck Brichory, Anne Vaslin Chessex, Ryan J Sullivan, Rachel B Keller, Sarah Denning, Emma R Hill, Geoffrey I Shapiro, Anna Pokorska-Bocci, Claudio Zanna, Kimmie Ng, Deborah Schrag, Pasi A Jänne, William C Hahn, Andrew D Cherniack, Ryan B Corcoran, Matthew Meyerson, Antoine Daina, Vincent Zoete, Nabeel Bardeesy, Brian M Wolpin
FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma. Cancer discovery 11 (10) (2021)
Haider Mahdi, Navid Hafez, Deborah B Doroshow, Davendra Sohal, Vickie Keedy, Khanh T Do, Patricia LoRusso, Juliane Jürgensmeier, Manuel Avedissian, Jeffrey S Sklar, Colin Glover, Brunella Felicetti, Emma Dean, Peter G S Mortimer, Geoffrey I Shapiro, Joseph Paul Eder
Ceralasertib-Mediated ATR Inhibition Combined With Olaparib in Advanced Cancers Harboring DNA Damage Response and Repair Alterations (Olaparib Combinations). JCO precision oncology 5 (2021)
Panagiotis A Konstantinopoulos, Alexandre Andre Balieiro Anastacio da Costa, Doga Gulhan, Elizabeth K Lee, Su-Chun Cheng, Andrea E Wahner Hendrickson, Bose Kochupurakkal, David L Kolin, Elise C Kohn, Joyce F Liu, Elizabeth H Stover, Jennifer Curtis, Nabihah Tayob, Madeline Polak, Dipanjan Chowdhury, Ursula A Matulonis, Anniina Farkkila, Alan D' Andrea, Geoffrey I Shapiro
A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer. Nature communications 12 (1) (2021)
Mansoor N Saleh, Manish R Patel, Todd M Bauer, Sanjay Goel, Gerald S Falchook, Geoffrey I Shapiro, Ki Y Chung, Jeffrey R Infante, Robert M Conry, Guilherme Rabinowits, David S Hong, Judy S Wang, Ulrich Steidl, Gurudatta Naik, Vincent Guerlavais, Vojislav Vukovic, D Allen Annis, Manuel Aivado, Funda Meric-Bernstam
Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-Type TP53. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Khanh T Do, Bose Kochupurakkal, Sarah Kelland, Adrienne de Jonge, Jennifer Hedglin, Allison Powers, Nicholas Quinn, Courtney Gannon, Loan Vuong, Kalindi Parmar, Jean-Bernard Lazaro, Alan D' Andrea, Geoffrey I Shapiro
Phase 1 Combination Study of the CHK1 Inhibitor Prexasertib and the PARP Inhibitor Olaparib in High-grade Serous Ovarian Cancer and Other Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (17) (2021)
Geoffrey I Shapiro, Robert Wesolowski, Craig Devoe, Simon R Lord, John Pollard, Bart S Hendriks, Martin Falk, Ivan Diaz-Padilla, Ruth Plummer, Timothy Anthony Yap
Phase 1 study of the ATR inhibitor berzosertib in combination with cisplatin in patients with advanced solid tumours. British journal of cancer 125 (4) (2021)
James M Cleary, Brian M Wolpin, Stephanie K Dougan, Srivatsan Raghavan, Harshabad Singh, Brandon M Huffman, Nilay S Sethi, Jonathan A Nowak, Geoffrey I Shapiro, Andrew J Aguirre, Alan D' Andrea
Opportunities for Utilization of DNA Repair Inhibitors in Homologous Recombination Repair-Deficient and Proficient Pancreatic Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
William D Tap, Arun S Singh, Stephen Patrick Anthony, Mike Sterba, Chao Zhang, John H Healey, Bartosz Chmielowski, Allen Lee Cohn, Geoffrey I Shapiro, Vicki L Keedy, Zev A Wainberg, Igor Puzanov, Gregory M Cote, Andrew J Wagner, Fadi Braiteh, Eric Sherman, Henry H Hsu, Charles Peterfy, Heather L Gelhorn, Xin Ye, Paul Severson, Brian L West, Paul S Lin, Sandra Tong-Starksen
Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Panagiotis A Konstantinopoulos, Su-Chun Cheng, Jeffrey G Supko, Madeline Polak, Andrea E Wahner-Hendrickson, S Percy Ivy, Brittany Bowes, Hannah Sawyer, Patrice Basada, Martin Hayes, Jennifer Curtis, Neil Horowitz, Alexi A Wright, Susana M Campos, Elena V Ivanova, Cloud P Paweletz, Sangeetha Palakurthi, Joyce F Liu, Alan D' Andrea, Prafulla C Gokhale, Dipanjan Chowdhury, Ursula A Matulonis, Geoffrey I Shapiro
Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours. British journal of cancer (2021)
Mark R Middleton, Emma Dean, Thomas R J Evans, Geoffrey I Shapiro, John Pollard, Bart S Hendriks, Martin Falk, Ivan Diaz-Padilla, Ruth Plummer
Phase 1 study of the ATR inhibitor berzosertib (formerly M6620, VX-970) combined with gemcitabine ± cisplatin in patients with advanced solid tumours. British journal of cancer 125 (4) (2021)
Geoffrey I Shapiro, Patricia LoRusso, Daniel C Cho, Luna Musib, Yibing Yan, Matthew Wongchenko, Ilsung Chang, Premal Patel, Iris T Chan, Sandra Sanabria-Bohorquez, Raymond D Meng, Johanna C Bendell
A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors. Investigational new drugs 39 (1) (2020)
Geoffrey I Shapiro, Patricia LoRusso, Afshin Dowlati, Khanh T Do, Caron A Jacobson, Ulka Vaishampayan, Amy Weise, Paolo F Caimi, Joseph Paul Eder, Christopher A French, Emily Labriola-Tompkins, Frédéric Boisserie, William E Pierceall, Jianguo Zhi, Sharon Passe, Mark DeMario, Martin Kornacker, Philippe Armand
A Phase 1 study of RO6870810, a novel bromodomain and extra-terminal protein inhibitor, in patients with NUT carcinoma, other solid tumours, or diffuse large B-cell lymphoma. British journal of cancer 124 (4) (2020)
Sarina A Piha-Paul, Christine L Hann, Christopher A French, Sophie Cousin, Irene Braña, Phillippe A Cassier, Victor Moreno, Johann S de Bono, Sara Duckworth Harward, Geraldine Ferron-Brady, Olena Barbash, Anastasia Wyce, Yuehui Wu, Thierry Horner, Meg Annan, Nigel J Parr, Rabinder K Prinjha, Christopher L Carpenter, John Hilton, David S Hong, Naomi B Haas, Mark C Markowski, Arindam Dhar, Peter J O'Dwyer, Geoffrey I Shapiro
Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors. JNCI cancer spectrum 4 (2) (2019)
Nicole G Chau, Clement Ma, Kristina Danga, Hasan Al-Sayegh, Valentina Nardi, Ryan Barrette, Christopher S Lathan, Steven G DuBois, Robert I Haddad, Geoffrey I Shapiro, Stephen E Sallan, Arindam Dhar, Jeanenne J Nelson, Christopher A French
An Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients. JNCI cancer spectrum 4 (2) (2019)

Geoffrey I Shapiro.css-eqlu8i{font-size:small;padding-left:4px;} (Geoffrey Shapiro)

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Geoffrey I Shapiro (Geoffrey Shapiro)