High red blood cell distribution width attenuates the effectiveness of Immune checkpoint inhibitor therapy: An exploratory study using a clinical data warehouse.

Hiromi MatsumotoTaichi FukushimaNobuaki KobayashYuuki HigashinoSuguru MuraokaYukiko OhtsuMomo HirataKohei SomekawaAyami KanekoRyo NagasawaSousuke KuboKatsushi TanakaKota MurohashiHiroaki FujiiKeisuke WatanabeNobuyuki HoritaYu HaraTakeshi Kaneko

Published in: PloS one (2024)

This study suggests the utility of CDWs in identifying prognostic biomarkers for ICI therapy in cancer treatment. Elevated RDW before treatment initiation emerged as a potential biomarker of shorter therapy duration.

Keyphrases

red blood cell
randomized controlled trial
big data
mesenchymal stem cells
bone marrow
cell therapy