Is surgery the fair competitor for MitraClip?
Michele Di MauroEliana RaviolaStefano GuarraciniMassimo Di MarcoRoberto LorussoAntonio Maria CalafiorePublished in: Journal of cardiac surgery (2021)
In the last decades, the overlapping areas of intervention between cardiac surgeons and interventional cardiologists are rocketing, especially in the field of treatment of heart valve disease. But, while for the aortic valve the competition, even for nonhigh risk patients, has become tightened, in the context of mitral regurgitation, the surgery seems to not have competitors. In fact looking the results of studies published so far, a question arises: Is surgery the fair competitor for the Mitraclip? The meta-analysis by Abdul Khader et al. summarized few evidences present in this field, only 11 observational studies and 1 randomized trial, providing an awesome response: "NO." Is therefore not a case if recently two trials, MITRA-FR and COAPT, chose to use as competitor for MitraClip, more rightly, medical therapy instead of surgery. In conclusions, in case of mitral regurgitation (MR), surgery is still largely the gold standard treatment and so MitraClip cannot be mention at all as competitor of surgery. It can be the right choice of case of primary MR where patients showed high risk for surgery. In case of secondary MR, especially with large and poor left ventricle we should wait for a clear answer on its role, yet.
Keyphrases
- minimally invasive
- coronary artery bypass
- mitral valve
- aortic valve
- end stage renal disease
- systematic review
- surgical site infection
- chronic kidney disease
- healthcare
- ejection fraction
- newly diagnosed
- randomized controlled trial
- stem cells
- computed tomography
- heart failure
- magnetic resonance imaging
- peritoneal dialysis
- aortic stenosis
- coronary artery disease
- aortic valve replacement
- bone marrow
- transcatheter aortic valve replacement
- patient reported outcomes
- acute coronary syndrome
- atrial fibrillation
- coronary artery
- meta analyses
- decision making
- congenital heart disease