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Resolution of Acute Priapism in Two Children With Sickle Cell Disease Who Received Nitrous Oxide.

Michael H GreenwaldColleen K GutmanClaudia R Morris
Published in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2019)
Priapism is a challenging complication of SCD associated with long-term morbidity and a paucity of treatment options. Opioids are commonly used. Given the risks and inconsistent results of current recommended therapy, N2 O may represent a potential opioid-sparing treatment option for priapism presenting to the ED that warrants further investigation. Although anecdotal, N2 O inhalation is an intervention to consider during a time when a treating ED physician may have few alternatives.
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