Bilateral Oophorectomy and the Risk of Breast Cancer in BRCA1 Mutation Carriers: A Reappraisal.
Joanne KotsopoulosJan LubinskiJacek GronwaldJanusz MenkiszakJeanna McCuaigKelly MetcalfeWilliam D FoulkesSusan L NeuhausenSophie SunBeth Y KarlanAndrea EisenNadine TungOlufunmilayo I OlopadeFergus J CouchTomasz HuzarskiLeigha SenterLouise BordeleauChristian F SingerCharis EngRobert FruscioTuya PalPing SunSteven A NarodPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2022)
Oophorectomy is unlikely a determinant of breast cancer risk in BRCA1 mutation carriers but should be offered at age 35 to reduce the risk of ovarian and fallopian tube cancer.