Comprehensive multicomponent characterization and quality assessment of Shuang-Huang-Lian powder injection by UHPLC-QTOF-MS and UHPLC-Q-Orbitrap-MS.

Jiaxin YinChao LiJie ZhangHui DingLifeng HanWenzhi YangFangyi LiXinbo SongSongtao BieHeshui YuZheng Li

Published in: Rapid communications in mass spectrometry : RCM (2023)

This work comprehensively characterized the material basis of SHLPI, summarized the cracking laws of representative substances, and quantitatively analyzed 10 potential allergenic components. Therefore, this study could provide a basis for the quality control of SHLPI and the clinical rational use of drugs to reduce its adverse reactions.

Keyphrases

ms ms
quality control
mass spectrometry
ultra high performance liquid chromatography
high resolution mass spectrometry
high resolution
multiple sclerosis
liquid chromatography
drinking water
simultaneous determination
cross sectional
emergency department
risk assessment
solid phase extraction