Induction Toripalimab And Chemotherapy For Organ Preservation In Locally Advanced Laryngeal And Hypopharyngeal Cancer: A Single-Arm Phase 2 Clinical Trial.

Xiaomin Ou Ruiping Zhai Wenjun Wei Jiaying Chen Dan Ou Tian Liao Tingting Xu Yongxue Zhu Yu-Long Wang Shenglin Huang Rongliang Shi Bin Wu Tongzhen Chen Yuan Li Zhongyi Yang Changming Zhou Yuan Liu Ziting Jiang Min Zeng Xin Liu Dongmei Ji Hong-Mei Ying Zhen Zhang Chaosu Hu Xueguan Lu Qinghai Ji Xiayun He Yu Wang

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

Induction toripalimab combined with chemotherapy provided encouraging activity, promising larynx preservation rate and acceptable toxicity in this cohort of extensively locally advanced laryngeal and hypopharyngeal cancer.

Keyphrases

locally advanced
rectal cancer
neoadjuvant chemotherapy
squamous cell carcinoma
papillary thyroid
radiation therapy
clinical trial
phase ii study
squamous cell
multidrug resistant
randomized controlled trial
young adults
open label
lymph node
phase ii
chemotherapy induced