C-reactive protein across pregnancy in individuals exposed to childhood maltreatment: The role of psychological and physical sequelae of maltreatment.
Theresa S KleihLauren S Keenan-DevlinSonja EntringerNina SpägeleMalvika GodaraChristine M HeimNorbert KathmannWilliam GrobmanHyagriv SimhanAnn E B BordersPathik D WadhwaClaudia BussPublished in: Brain, behavior, and immunity (2024)
These results add to the growing empirical evidence suggesting higher inflammation during pregnancy in participants exposed to CM who experience depressive symptoms and highlight the detrimental effects of multiple co-occurring experiences of maltreatment. Given the negative consequences of chronic inflammatory state for the mother and the developing fetus, monitoring and treating psychiatric sequelae during pregnancy among participants exposed to CM is potentially an important opportunity to dampen long-term detrimental effects of CM, serving at least two generations.