Utilization of a Cortical Xenogeneic Membrane for Guided Bone Regeneration: A Retrospective Case Series.
Cyril DebortoliArthur FalguièreFabrice CampanaJean-Hugues CatherineDelphine TardivoRomain LanPublished in: Journal of clinical medicine (2024)
Background : Guided bone regeneration (GBR) is a reliable technique used in vertical and horizontal bone defects. The posterior mandibular region is an area limited by anatomic constraints. The use of resorbable membranes with a cortical component could compensate for the lack of rigidity of resorbable membranes without the complications of non-resorbable membranes. The aim of this study was to evaluate the mean bone gains of a xenogeneic cortical membrane in horizontal and vertical bone defects in comparison with other membranes in the literature. Methods : A porcine cortical membrane was used to perform 7 GBR in the posterior mandibular region of five patients. Preoperative (T0) and six months postoperative (T1) cone beam computed tomography were superimposed to measure the horizontal and vertical bone gain. Implants were positioned at all sites, six months after GBR. Complications and bone resorption around the implants were also documented. Results : The mean horizontal and vertical bone gains were 3.83 ± 1.41 mm and 4.17 ± 1.86 mm, respectively. The analysis of repeatability was 0.997. As many as 40% of patients experienced pain refractory to analgesics. No exposure or infectious phenomenon was observed. Conclusions : This xenogeneic cortical membrane seemed to provide interesting results in the regeneration of horizontal and vertical bone defects. Comparative and prospective studies are necessary to validate the effectiveness of this membrane.
Keyphrases
- bone regeneration
- bone mineral density
- soft tissue
- bone loss
- end stage renal disease
- ejection fraction
- cone beam computed tomography
- stem cells
- randomized controlled trial
- newly diagnosed
- peritoneal dialysis
- patients undergoing
- prognostic factors
- risk factors
- patient reported outcomes
- neuropathic pain
- clinical evaluation