Safety and Efficacy of Poseltinib, Bruton's Tyrosine Kinase Inhibitor, in Patients With Rheumatoid Arthritis: A Randomized, Double-blind, Placebo-controlled, 2-part Phase II Study.
Mark C GenoveseAlberto SpindlerAkira SagawaWon ParkAnna DudekAlan KivitzJeannie ChaoLai Shan Melanie ChanJennifer WitcherWilliam BarchukAjay NirulaPublished in: The Journal of rheumatology (2020)
While no safety findings precluded continuation, the study was terminated after interim data demonstrated low likelihood of benefit in RA.