A preliminary study of the effect of naldemedine tosylate on opioid-induced nausea and vomiting.

Junya SatoRei TanakaHiroshi IshikawaTsutomu SuzukiMichihiro Shino

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2019)

For patients with constipation, using NALD at an early stage of opioid initiation might have secondary benefits, such as relief from OINV, besides improvement of OIC. To confirm the effectiveness of NALD for OINV, the symptom grade and intensity during concomitant use of NALD should be observed in a future study.

Keyphrases

early stage
chronic pain
pain management
randomized controlled trial
high glucose
high intensity
current status
radiation therapy
endothelial cells
stress induced
locally advanced
rectal cancer
abdominal pain