Varying Definitions of Carotid Intima-Media Thickness and Future Cardiovascular Disease: A Systematic Review and Meta-Analysis.
Yong LingYiming WanEmma A Barinas-MitchellAkira FujiyoshiHui CuiAikedan MaimaitiRong XuJing LiChen SuoMaryam ZaidPublished in: Journal of the American Heart Association (2023)
Combined-IMT is more strongly associated with CVD events compared with single-segment cIMT definitions. Maximum CCA-IMT shows a stronger association with MI than mean CCA-IMT. Further research is warranted to validate our findings and to standardize the cIMT measurement protocol, as well as to explore underlying mechanisms.