Impact of tailored multimodal treatment for unruptured brain arteriovenous malformation: comparison with a randomized trial of unruptured brain arteriovenous malformations.
Taichi IkedoEtsuko Hattori YamamotoHisae MoriAkihiro NiwaSaya OzakiYuji KushiKoji ShimonagaEika HamanoKiyofumi YamadaHirotoshi ImamuraKoji IiharaHiroharu KataokaPublished in: Acta neurochirurgica (2023)
The therapeutic intervention rate did not decrease, even after the publication of the ARUBA trial. The rate of stroke or death was lower in the intervention group, indicating that a tailored choice of multimodality is safe and effective for managing unruptured bAVM.
Keyphrases
- middle cerebral artery
- internal carotid artery
- randomized controlled trial
- resting state
- white matter
- cerebral ischemia
- study protocol
- smoking cessation
- atrial fibrillation
- functional connectivity
- clinical trial
- phase iii
- endovascular treatment
- multiple sclerosis
- replacement therapy
- brain injury
- chronic pain
- blood brain barrier
- decision making
- open label