Effect of Antihypertensives by Class on Cerebral Small Vessel Disease: A Post Hoc Analysis of SPRINT-MIND.

Eric D Goldstein Zoe WolcottGauri GargKayla NavarroAlen DelicShadi Yaghi Benson Sederholm Shyam Prabhakaran Ka-Ho WongKaitlin McLeanAdam H de Havenon

Published in: Stroke (2022)

Among participants of SPRINT-MIND trial, angiotensin-converting enzyme inhibitor was most consistently associated with less WMH progression independent of blood pressure control and age.

Keyphrases

angiotensin converting enzyme
blood pressure
angiotensin ii
high intensity
resistance training
study protocol
phase iii
subarachnoid hemorrhage
clinical trial
hypertensive patients
phase ii
heart rate
randomized controlled trial
metabolic syndrome
blood brain barrier
weight loss
skeletal muscle