A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection.

Published in: Science immunology (2024)

Upon SARS-CoV-2 infection, infected cells undergo necroptosis, whereas delayed apoptosis and pyroptosis occur in uninfected, bystander cells, thus providing a plausible explanation for the extensive injury among myriad uninfected cells.

Keyphrases

cell cycle arrest
cell death
induced apoptosis
endoplasmic reticulum stress
pi k akt
oxidative stress
hiv infected
signaling pathway
sars cov
respiratory syndrome coronavirus