Lok-Yin Roy Wong

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 23

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Nature

Journal of virology

University of Iowa

University of Hong Kong (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Iowa Jul 01 2019

United States

Post-doctoral Scholar :: Microbiology and Immunology

University of Hong Kong Jan 01 2019 - Jun 30 2019

Hong Kong

Research Assistant :: School of Biomedical Sciences

Education History

University of Hong Kong Sep 01 2014 - Aug 31 2018

Hong Kong

PHD :: School of Biomedical Sciences

University of Hong Kong Sep 01 2011 - Jun 30 2014

Hong Kong

BSC :: Biochemistry

Publications

Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Shea A Lowery, Noah Schuster, Lok-Yin Roy Wong, Thomas Carrillo, Erin Peters, Abby Odle, Alan Sariol, Isabella Cesarz, Pengfei Li, Stanley Perlman
Mouse hepatitis virus JHMV I protein is required for maximal virulence. Journal of virology (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Lok-Yin Roy Wong, Stanley Perlman
A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection. Science immunology 9 (97) (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Stacey M Hartwig, Abby Odle, Lok-Yin Roy Wong, David K Meyerholz, Stanley Perlman, Steven M Varga
Respiratory syncytial virus infection provides protection against severe acute respiratory syndrome coronavirus challenge. Journal of virology (2024)
Pengfei Li, Biyun Xue, Nicholas J Schnicker, Lok-Yin Roy Wong, David K Meyerholz, Stanley Perlman
Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence. Proceedings of the National Academy of Sciences of the United States of America 120 (31) (2023)
Lok-Yin Roy Wong, Abby Odle, Emma Luhmann, Douglas C Wu, Yiquan Wang, Qi Wen Teo, Celeste Ptak, Alan Sariol, Shea Lowery, Matthias Mack, David K Meyerholz, Nicholas C Wu, Lilliana Radoshevich, Stanley Perlman
Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice. mBio (2023)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Tom Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. bioRxiv : the preprint server for biology (2023)
Karen V Kibler, Mateusz Szczerba, Douglas Lake, Alexa J Roeder, Masmudur M Rahman, Brenda G Hogue, Lok-Yin Roy Wong, Stanley Perlman, Yize Li, Bertram L Jacobs
Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501Y MA30 Strain of SARS-CoV-2. Vaccines 10 (8) (2022)
Lok-Yin Roy Wong, Stanley Perlman
Proviral role of caspase-6 in coronavirus infections. Cell research (2022)
Lok-Yin Roy Wong, Jian Zheng, Kevin Wilhelmsen, Kun Li, Miguel E Ortiz, Nicholas J Schnicker, Andrew Thurman, Alejandro A Pezzulo, Peter J Szachowicz, Pengfei Li, Ruangang Pan, Klaus Klumpp, Fred Aswad, Justin Rebo, Shuh Narumiya, Makoto Murakami, Sonia Zuñiga, Isabel Sola, Luis Enjuanes, David K Meyerholz, Kristen Fortney, Paul B McCray, Stanley Perlman
Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19. Nature 605 (7908) (2022)
Lok-Yin Roy Wong, Jian Zheng, Alan Sariol, Shea Lowery, David K Meyerholz, Tom Gallagher, Stanley Perlman
Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence. Proceedings of the National Academy of Sciences of the United States of America 118 (24) (2021)
Chamandi S Dampalla, Jian Zheng, Krishani Dinali Perera, Lok-Yin Roy Wong, David K Meyerholz, Harry Nhat Nguyen, Maithri M Kashipathy, Kevin P Battaile, Scott Lovell, Yunjeong Kim, Stanley Perlman, William C Groutas, Kyeong-Ok Chang
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America 118 (29) (2021)
Lok-Yin Roy Wong, Stanley Perlman
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses - are we our own worst enemy? Nature reviews. Immunology (2021)
Lok-Yin Roy Wong, Zi-Wei Ye, Pak-Yin Lui, Xuyang Zheng, Shuo-Feng Yuan, Lin Zhu, Sin-Yee Fung, Kit-San Yuen, Kam-Leung Siu, Man-Lung Yeung, Zongwei Cai, Patrick Chiu-Yat Woo, Kwok-Yung Yuen, Chi-Ping Chan, Dong-Yan Jin
Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε. Journal of immunology (Baltimore, Md. : 1950) 205 (6) (2020)
Jian Zheng, Lok-Yin Roy Wong, Kun Li, Abhishek Kumar Verma, Miguel E Ortiz, Christine Wohlford-Lenane, Mariah R Leidinger, C Michael Knudson, David K Meyerholz, Paul B McCray, Stanley Perlman
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Nature 589 (7843) (2020)
Pak-Yin Lui, Lok-Yin Roy Wong, Ting-Hin Ho, Shannon Wing Ngor Au, Chi-Ping Chan, Raven K H Kok, Dong-Yan Jin
PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization. Journal of immunology (Baltimore, Md. : 1950) 199 (5) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Lok-Yin Roy Wong