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Nanoparticles in Clinical Translation for Cancer Therapy.

Deepa MundekkadWilliam Chi Shing Cho
Published in: International journal of molecular sciences (2022)
The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner. This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment. The obstacles in the journey of nanodrug from clinic to market are reviewed. Furthermore, the latest developments in using nanoparticles in cancer therapy are also highlighted.
Keyphrases
  • cancer therapy
  • drug delivery
  • clinical trial
  • primary care
  • drug release
  • randomized controlled trial
  • squamous cell carcinoma
  • papillary thyroid