Development and evaluation of a multiplex loop-mediated isothermal amplification (LAMP) assay for differentiation of Mycobacterium tuberculosis and non-tuberculosis mycobacterium in clinical samples.

Jeeyong Kim Borae G ParkDa Hye LimWoong Sik JangJeonghun NamDo-CiC MihnChae Seung Lim

Published in: PloS one (2021)

Our newly designed multiplex LAMP assay for MTB and NTM showed relatively good sensitivity in comparison with previously published data to detect isolated MTB. This multiplex LAMP assay is expected to become a useful tool for detecting and differentiating MTB from NTM rapidly at an acceptable sensitivity.

Keyphrases

mycobacterium tuberculosis
loop mediated isothermal amplification
high throughput
pulmonary tuberculosis
sensitive detection
real time pcr
single cell
randomized controlled trial
electronic health record
systematic review
computed tomography
machine learning
emergency department
quantum dots
data analysis