Associations of neuroimaging markers with depressive symptoms over time in middle-aged and elderly persons.

Fatih ÖzelSaima HilalMaud de FeijterIsabelle van der VelpenNese DirekM Arfan IkramMeike W VernooijAnnemarie I Luik

Published in: Psychological medicine (2022)

Neuroimaging markers of white matter microstructural damage were associated with depressive symptoms longitudinally in this study of middle-aged and elderly persons. These associations were more pronounced at older ages, providing evidence for the role of white matter structure in late-life depressive symptomatology.

Keyphrases

white matter
depressive symptoms
community dwelling
middle aged
multiple sclerosis
social support
oxidative stress
sleep quality
bipolar disorder
physical activity