Association between concomitant proton pump inhibitor use and survival of patients with metastatic prostate cancer receiving abiraterone acetate: a post-hoc analysis of pooled data from three randomized controlled trials.

Wataru FukuokayaKeiichiro MoriShahrokh F ShariatKohei AkazawaTatsuya ShimomuraTakahiro Kimura

Published in: Prostate cancer and prostatic diseases (2023)

PPI use may be associated with inferior survival in patients with metastatic prostate cancer who receive ADT plus AAP. Discontinuing unnecessary PPI use might improve those outcomes.

Keyphrases

prostate cancer
radical prostatectomy
randomized controlled trial
protein protein
free survival
electronic health record
clinical trial
big data
machine learning
small molecule
metabolic syndrome
study protocol
data analysis
meta analyses
placebo controlled