Beta-hydroxy-beta-methylbutyrate supplementation and functional outcomes in multitrauma patients: A pilot randomized controlled trial.

Kym Wittholz Kate FetterplaceAmalia KarahaliosYasmine Ali AbdelhamidLisa BeachDavid ReadRené KoopmanJeffrey J PresneillAdam M Deane

Published in: JPEN. Journal of parenteral and enteral nutrition (2023)

A blinded, placebo-controlled, randomized clinical trial of daily enteral HMB supplementation for up to 28 days in hospital is feasible. Any effect of HMB supplementation to attenuate muscle wasting after traumatic injury remains uncertain.

Keyphrases

study protocol
randomized controlled trial
placebo controlled
end stage renal disease
double blind
ejection fraction
newly diagnosed
chronic kidney disease
healthcare
spinal cord injury
peritoneal dialysis
skeletal muscle
emergency department
physical activity
radiation therapy
phase ii
phase ii study
drug induced