Odontogenic gene expression profile of human dental pulp-derived cells under high glucose influence: a microarray analysis.

Sivaporn HorsophonphongHathaitip SritanaudomchaiSiriruk NakornchaiNakarin KitkumthornRudee Surarit

Published in: Journal of applied oral science : revista FOB (2021)

The high-glucose condition significantly inhibited the mineralization of hDPCs. DEGs were identified, and interestingly, HAS1 and Fbln-7 genes may be involved in the glucose inhibitory effect on hDPC mineralization.

Keyphrases

high glucose
endothelial cells
gene expression
induced apoptosis
dna methylation
cell cycle arrest
genome wide
blood pressure
oxidative stress
type diabetes
skeletal muscle
signaling pathway
pluripotent stem cells
induced pluripotent stem cells
insulin resistance
genome wide analysis
weight loss