Autophagy Suppresses Invasiveness of Endometrial Cells through Reduction of Fascin-1.

Xiaomei LuoWei ChengShizhang WangZhihong Chen Jieqiong Tan

Published in: BioMed research international (2018)

Our results indicate that the inhibition of autophagy and exogenous expression of fascin-1 may promote the invasiveness of endometrial cells. As a corollary, autophagy represents a potential target for the treatment of EM.

Keyphrases

induced apoptosis
endoplasmic reticulum stress
signaling pathway
cell death
cell cycle arrest
oxidative stress
poor prognosis
endometrial cancer
pi k akt
binding protein
replacement therapy