Efficacy and Safety of Liraglutide in Patients With an Ileal Pouch-Anal Anastomosis and Chronic High Bowel Frequency: A Placebo-Controlled, Crossover, Proof-of-Concept Study.
Hans H HerfarthMillie D LongJonathan J HansenChelsea AndersonEmily EnglishJohn B BuseEdward L BarnesPublished in: The American journal of gastroenterology (2024)
Larger randomized controlled studies are warranted to delineate the treatment potential of GLP-1 receptor agonists in IPAA patients suffering from noninflammatory high BF.
Keyphrases
- placebo controlled
- double blind
- end stage renal disease
- open label
- phase ii
- newly diagnosed
- phase iii
- ejection fraction
- chronic kidney disease
- clinical trial
- peritoneal dialysis
- prognostic factors
- study protocol
- randomized controlled trial
- risk assessment
- patient reported outcomes
- radiation therapy
- high grade
- human health
- case control
- climate change
- smoking cessation