Effectiveness of bevacizumab in first- and second-line treatment for metastatic colorectal cancer: ITACa randomized trial.

Elisabetta PetracciEmanuela ScarpiAlessandro PassardiAnnibale BiggeriCarlo MilandriStefano VecchiaFabio GelsominoDavide TassinariStefano TamberiIlaria BernardiniCaterina AccetturaGiovanni Luca FrassinetiDino AmadoriOriana Nanni

Published in: Therapeutic advances in medical oncology (2020)

Our results seem to suggest that B confers a PFS advantage when administered in combination with second-line chemotherapy, which could help to improve current international guidelines on optimal sequential treatment strategies.

Keyphrases

metastatic colorectal cancer
randomized controlled trial
systematic review
locally advanced
squamous cell carcinoma
combination therapy
radiation therapy