Sleep Disruption, Fatigue, and Depression as Predictors of 6-Year Clinical Outcomes Following Allogeneic Hematopoietic Cell Transplantation.
Kelly E RentscherJudith E CarrollMark B JuckettChristopher L CoeAimee Teo BromanPaul J RathouzPeiman HemattiErin S CostanzoPublished in: Journal of the National Cancer Institute (2022)
Biobehavioral symptoms, particularly sleep disruption and fatigue interference, predicted an increased risk for 6-year relapse and mortality after HCT. Because these symptoms are amenable to treatment, they offer specific targets for intervention to improve HCT outcomes.