Sleep Disruption, Fatigue, and Depression as Predictors of 6-Year Clinical Outcomes Following Allogeneic Hematopoietic Cell Transplantation.

Kelly E Rentscher Judith E Carroll Mark B Juckett Christopher L Coe Aimee Teo BromanPaul J RathouzPeiman HemattiErin S Costanzo

Published in: Journal of the National Cancer Institute (2022)

Biobehavioral symptoms, particularly sleep disruption and fatigue interference, predicted an increased risk for 6-year relapse and mortality after HCT. Because these symptoms are amenable to treatment, they offer specific targets for intervention to improve HCT outcomes.

Keyphrases

sleep quality
depressive symptoms
physical activity
stem cell transplantation
randomized controlled trial
cell cycle arrest
bone marrow
type diabetes
cell death
low dose
high dose
weight loss
smoking cessation