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Sleep Disruption, Fatigue, and Depression as Predictors of 6-Year Clinical Outcomes Following Allogeneic Hematopoietic Cell Transplantation.

Kelly E RentscherJudith E CarrollMark B JuckettChristopher L CoeAimee Teo BromanPaul J RathouzPeiman HemattiErin S Costanzo
Published in: Journal of the National Cancer Institute (2022)
Biobehavioral symptoms, particularly sleep disruption and fatigue interference, predicted an increased risk for 6-year relapse and mortality after HCT. Because these symptoms are amenable to treatment, they offer specific targets for intervention to improve HCT outcomes.
Keyphrases
  • sleep quality
  • depressive symptoms
  • physical activity
  • stem cell transplantation
  • randomized controlled trial
  • cell cycle arrest
  • bone marrow
  • type diabetes
  • cell death
  • low dose
  • high dose
  • weight loss
  • smoking cessation