Lifestyle interventions for the prevention of T2DM have been suggested to be effective. There is evidence of ethnic differences in some glycaemic and anthropometric outcomes. The meta-analysis suggested a significant result in reducing waist circumference (standardised mean difference - 019, 95%CI ( -0.31, -0.06)), and no significant effects in other outcomes. However, the implementation outcomes suggested lifestyle intervention might be a cost-effective and sustainable approach in T2DM particularly in countries in the Asia Pacific Region. The focus of lifestyle intervention in the Asia Pacific Region should not only lie in the effectiveness of the trial but a thorough evaluation of the implementation outcomes, as well as cultural adaptations, with the support of all stakeholders through all stages of the implementation.
Keyphrases
- type diabetes
- randomized controlled trial
- metabolic syndrome
- physical activity
- systematic review
- insulin resistance
- glycemic control
- primary care
- cardiovascular disease
- healthcare
- weight loss
- body mass index
- quality improvement
- clinical trial
- study protocol
- high fat diet
- body weight
- open label
- phase iii
- case control
- placebo controlled