Increased Serum Interleukin-2 Levels Are Associated with Abnormal Peripheral Blood Natural Killer Cell Levels in Patients with Active Rheumatoid Arthritis.
Baochen LiQiaoling GuoYanyan WangRui SuChong GaoJinfang ZhaoXiaofeng LiCai-Hong WangPublished in: Mediators of inflammation (2020)
In RA patients, serum IL-2 levels were not only correlated with patients' disease activity and autoantibody levels but were also involved in their Th17/Treg immune imbalance. In addition, in patients with active RA, NK cell levels were abnormally elevated, possibly due to high serum levels of IL-2.
Keyphrases
- rheumatoid arthritis
- disease activity
- end stage renal disease
- ejection fraction
- newly diagnosed
- ankylosing spondylitis
- systemic lupus erythematosus
- peripheral blood
- chronic kidney disease
- rheumatoid arthritis patients
- nk cells
- peritoneal dialysis
- stem cells
- cell therapy
- juvenile idiopathic arthritis
- single cell
- bone marrow
- interstitial lung disease
- mesenchymal stem cells
- systemic sclerosis
- patient reported