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A Systematic Review of Animal Models of NAFLD Finds High-Fat, High-Fructose Diets Most Closely Resemble Human NAFLD.

Yu Ri ImHarriet HunterDana de Gracia HahnAmedine DuretQinrong CheahJiawen DongMadison FaireyClarissa HjalmarssonAlice LiHong Kai LimLorcán McKeownClaudia-Gabriela MitrofanRaunak RaoMrudula UtukuriDenis MoirJake Peter Mann
Published in: Hepatology (Baltimore, Md.) (2021)
This systematic analysis provides a framework for phenotypic assessment of NAFLD models and highlights the need for increased standardization and replication.
Keyphrases
  • endothelial cells
  • weight loss
  • induced pluripotent stem cells
  • pluripotent stem cells
  • clinical evaluation
  • data analysis