Identifying lupus Patient Subsets Through Immune Cell Deconvolution of Gene Expression Data in Two Atacicept Phase II Studies.

Matthew StudhamCristina Vazquez-MateoEileen SamyPhilipp HaselmayerAida AydemirP Alexander RolfeJoan T Merrill Eric F MorandJulie DeMartinoAmy KaoRobert Townsend

Published in: ACR open rheumatology (2023)

This exploratory analysis indicates larger differences between placebo- and atacicept-treated patients with SLE in a molecularly defined patient subset.

Keyphrases

phase ii
gene expression
systemic lupus erythematosus
clinical trial
case report
disease activity
open label
dna methylation
phase iii
double blind
electronic health record
randomized controlled trial
machine learning
case control
newly diagnosed
study protocol