Placebo response and its predictors in Attention Deficit Hyperactivity Disorder: a meta-analysis and comparison of meta-regression and MetaForest.

Xavier CastellsMarc SaezMaghie BarcheniRuth CunillDomènec SerranoBeatriz LópezCaspar van Lissa

Published in: The international journal of neuropsychopharmacology (2021)

Strong placebo response was found in ADHD patients. Both meta-regression and MetaForest showed poor performance in predicting placebo response. ADHD symptom improvement with placebo has markedly increased over the last two decades and is grater in the US than the rest of the world.

Keyphrases

attention deficit hyperactivity disorder
autism spectrum disorder
working memory
double blind
end stage renal disease
phase iii
ejection fraction
newly diagnosed
chronic kidney disease
placebo controlled
randomized controlled trial
patient reported
clinical evaluation