Blood markers in remote ischaemic conditioning for acute ischaemic stroke: data from the REmote ischaemic Conditioning After Stroke Trial.

Jason Philip Appleton Saoirse Elizabeth O'SullivanAmanda HedstromJane A MayRichard DonnellyNikola Sprigg Philip M Bath Timothy J England

Published in: European journal of neurology (2020)

Remote ischaemic per-conditioning reduced SAP and TNF-α levels from pre- to post-intervention. Increases in plasma levels of SAP were associated with worse clinical outcomes after ischaemic stroke. Larger studies assessing biomarkers and the safety and efficacy of RIC in acute ischaemic stroke are warranted to further understand these relationships.

Keyphrases

liver failure
respiratory failure
randomized controlled trial
drug induced
aortic dissection
rheumatoid arthritis
clinical trial
study protocol
hepatitis b virus
electronic health record
big data
phase ii
intensive care unit
case control
placebo controlled