Evaluating the Relationship Between Lean Liver Volume and Fat-Free Mass.

Jaydeep SinhaStephen B DuffullBruce GreenHesham S Al-Sallami

Published in: Clinical pharmacokinetics (2021)

A model to predict lean liver volume from readily available patient data was developed and evaluated. Fat-free mass plus sex was found to be the best body descriptor to scale lean liver volume. The utility of this model in scaling drug clearance and dose requirements of hepatically cleared drugs needs further exploration.

Keyphrases

adipose tissue
bone mineral density
fatty acid
emergency department
drug induced
body composition
data analysis