Cerebrospinal fluid YKL-40 level evolution is associated with autoimmune encephalitis remission.
Guillaume DorcetMarie BenaiteauJérémie ParienteFabienne Ory-MagneEmmanuel CheuretMarie RafiqWesley BrooksBénédicte Puissant-LubranoFrançoise FortenfantYves RenaudineauChloé BostPublished in: Clinical & translational immunology (2023)
The concentration of YKL-40, a cytokine-like proinflammatory protein produced by glial cells, is correlated in the CSF with the clinical course of AIE. Its introduction as a biomarker may assist in following disease activity and in evaluating therapeutic response.
Keyphrases
- disease activity
- cerebrospinal fluid
- systemic lupus erythematosus
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- induced apoptosis
- juvenile idiopathic arthritis
- cell cycle arrest
- multiple sclerosis
- living cells
- protein protein
- fluorescent probe
- cell death
- endoplasmic reticulum stress
- amino acid
- small molecule
- single molecule
- cell proliferation