Geographic characteristics of HTLV-1 molecular subgroups and genetic substitutions in East Asia: Insights from complete genome sequencing of HTLV-1 strains isolated in Taiwan and Japan.

Satoshi NozumaAkiko YoshimuraShun-Chung PaiHung-Jen ChenEiji MatsuuraMasakazu TanakaDaisuke KodamaMika DozonoToshio MatsuzakiHiroshi TakashimaYa-Chien YangRyuji Kubota

Published in: PLoS neglected tropical diseases (2024)

The transcontinental subgroup of HTLV-1 is predominant in Taiwan, while the Japanese subgroup is common in Japan. The difference in subgroup distribution may be attributed to the initial spread of the transcontinental subgroup in East Asia, followed by the influx of the Japanese subgroup.

Keyphrases

phase iii
clinical trial
randomized controlled trial
single cell
gene expression
study protocol
high throughput sequencing