Intraoral granulocytic sarcoma as a manifestation of myelofibrosis: A case report and review of the literature.
Laiz Fernandes Mendes NunesAmanda Leal RochaGustavo Henrique Romani MagalhãesFrederico Henrique Corrêa de MeloDenise Vieira TravassosRicardo Alves MesquitaTarcília Aparecida da SilvaPublished in: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry (2018)
Granulocytic sarcoma (GS) is an extramedullary tumor associated with myelodysplastic syndromes or myeloproliferative diseases. Intraoral manifestations are considered uncommon, with a reasonable number of cases, and are mostly related to leukemia. The association of oral GS and myelofibrosis is very rare and only three cases have been published. In this paper, we report the fourth case of oral lesion in a patient with a diagnosis of myelofibrosis. The aim of this study was to present a review of the literature, discussing the current and previous cases of oral GS associated with myelofibrosis or other hematological disorders and the importance of accurate diagnosis through clinical, microscopic, and immunohistochemical features.