Effect of behavioral weight-loss program on biomarkers of cardiometabolic disease risk: Heart Health Study randomized trial.
Katherine A CollinsWilliam E KrausRenee J RogersElizabeth R HauserWei LangRong JiangErik B SchelbertKim M HuffmanJohn M JakicicPublished in: Obesity (Silver Spring, Md.) (2023)
All intervention groups prompted a notable beneficial change among biomarkers of insulin resistance and cardiometabolic health. However, the addition of at least moderate-intensity physical activity to a diet-only intervention did not provide any additional benefit. These findings highlight that an average weight loss of approximately 10% profoundly impacts biomarkers of insulin resistance and cardiometabolic disease in adults with overweight or obesity.
Keyphrases
- weight loss
- insulin resistance
- bariatric surgery
- physical activity
- roux en y gastric bypass
- gastric bypass
- healthcare
- randomized controlled trial
- public health
- metabolic syndrome
- adipose tissue
- glycemic control
- mental health
- skeletal muscle
- type diabetes
- weight gain
- polycystic ovary syndrome
- high fat diet induced
- high intensity
- heart failure
- health information
- obese patients
- body mass index
- health promotion
- depressive symptoms