Evaluating the Effectiveness and Safety of Evinacumab in Treating Hypercholesterolemia and Hypertriglyceridemia: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Hussain Sohail RangwalaHareer FatimaMirha AliMuhammad Ashir ShafiqBurhanuddin Sohail RangwalaVikash VirwaniAashish KumarSyed Ali ArsalAdarsh RajaSandesh RajaMuhammad Saqlain Mustafa

Published in: American journal of cardiovascular drugs : drugs, devices, and other interventions (2024)

High-dose evinacumab (15 mg) consistently demonstrated efficacy in reducing cholesterol and other lipid markers, with favorable tolerability. Further research is warranted to comprehensively assess its safety and clinical effectiveness, emphasizing the need for additional data to support its use in managing cardiovascular disease.

Keyphrases

high dose
cardiovascular disease
systematic review
low density lipoprotein
randomized controlled trial
low dose
cardiovascular events
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stem cell transplantation
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metabolic syndrome
cardiovascular risk factors
clinical trial
placebo controlled
deep learning