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Liposomal bupivacaine versus conventional anesthetic or placebo for hemorrhoidectomy: a systematic review and meta-analysis.

P Solis-PazminoL FigueroaK LaO TermeieK OkaM SchleicherJ CohenM BarnajianYosef Nasseri
Published in: Techniques in coloproctology (2024)
Comparing LB to conventional anesthetic/placebo anesthetic for hemorrhoidectomy, we found a statistically significant reduction in pain through 72 h, decreased opioid requirements, and delayed time to first opioid use. Moreover, the conventional anesthetic/placebo group reported more pain in bowel movement than LB groups.
Keyphrases
  • pain management
  • chronic pain
  • double blind
  • neuropathic pain
  • postoperative pain
  • randomized controlled trial
  • spinal cord injury
  • open label