Applicability of Western protocols in resource-limited setting: Real-world data of long-term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka.
Saman HewamanaLakmali KandabadageThurairajah SkandarajahNatasha PierisEranga PereraMahesh HarischandraAnanda WijewickramaChandana WickramarathnaGnani SomasundaramVadivelu SrinivasanSurjit SomiahPriyankara JayawardenaMehendra PereraDehan GunasekeraChathuri JayasingheGodvin ConstantineSanjeewa MunasingheChandu De SilvaBandula WijesiriwardenaJayantha BalawardenaPublished in: EJHaem (2021)
There are no published data on long-term survival and applicability of treatment protocols from developed countries in acute myeloid leukaemia (AML) in Sri Lanka. Eighty-seven AML patients were reviewed; there were 56 newly diagnosed patients between 18 and 65 years. Thirty-one out of 33 who started treatment achieved complete remission after first cycle of treatment. The induction mortality was one of 33. Twelve out of 20 patients who completed treatment are alive at the time of analysis. The estimated 5-year overall survival rate is 0.629. Strict infection control and treatment and superior clinical experience may have contributed towards better outcome.
Keyphrases
- newly diagnosed
- acute myeloid leukemia
- end stage renal disease
- type diabetes
- randomized controlled trial
- bone marrow
- systematic review
- machine learning
- coronary artery disease
- cardiovascular disease
- risk factors
- acute lymphoblastic leukemia
- intensive care unit
- electronic health record
- cardiovascular events
- aortic dissection