[Informative changes in indicators of homeostasis to the assessment of individual risk adaptation disorders in workers of the chemical industry.]

This paper reviews the results of complex laboratory examinations among workers manufacturing fiber glass. The most pronounced and early changes in oxidative metabolism processes (reduced catalase activity, increased malonic dialdehyde) and rates of blood serum lipid metabolism indicators were determined, increased values of leukocyte indices of intoxication, violations in the immune status. Changes were detected in workers even with a small length of service (5 years) and young age (20-30 years). With increasing length of service in the workplace, the frequency of these violations increased.Based on the data obtained we have developed laboratory markers that are suitable for diagnosing early preclinical disorders among fiber glass manufacturing workers.