Associations of immune checkpoint predictive biomarkers MHC-I and MHC-II with clinical and molecular features in a diverse breast cancer cohort.
Xiaopeng SunLaura C KennedyPaula I Gonzalez EricssonVioleta SanchezMelinda E SandersCharles M PerouMelissa A TroesterJustin M BalkoSonya A ReidPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
In this diverse study population, MHC-I and MHC-II tumor cell expression were more highly expressed in HR+/HER2- tumors from Black women, underscoring the importance of diverse and equitable enrollment in future IO trials.