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Decrease in Prevalence of Cleft lip, Alveolus and Palate After Nationwide Introduction of the Second-Trimester Anomaly Scan in the Netherlands.

Johannes A SmitCaroline J BaxChristl Vermeij-KeersBert A H TrenningBernadette S de BakkerCorstiaan C Breugem
Published in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (2023)
This study demonstrates a significant decrease in the prevalence of CL/A and CLAP after introduction of the SAS. However, due to an increase in CP, the prevalence of all patients born with OFCs has not changed in the Netherlands between 1997 and 2019.
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