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Severe oral mucositis relating to pain and worse oral condition among patients with solid tumors undergoing treatment with FOLFIRI and 5-FU: a retrospective study.

Laura Costa de AlmeidaBernardo da Fonseca OrcinaAloizio Premoli MacielDayanne Simões Ferreira SantosBrena Rodrigues ManzanoPaulo Sérgio da Silva Santos
Published in: Sao Paulo medical journal = Revista paulista de medicina (2022)
Individuals with tumors who presented severe OM had greater severity of oral pain and worse oral health. Use of the FOLFIRI protocol was associated with higher prevalence of severe OM, while use of 5-fluorouracil (5-FU) was correlated with worse oral condition.
Keyphrases
  • chronic pain
  • early onset
  • oral health
  • neuropathic pain
  • randomized controlled trial
  • metastatic colorectal cancer
  • drug induced
  • radiation induced
  • wild type
  • smoking cessation