An in vitro study on anti-carcinogenic effect of remdesivir in human ovarian cancer cells via generation of reactive oxygen species.

Chang Min LeeMi-Ae KangJun Sang BaeKyungmoon ParkYung-Hun YangJongsung LeeKyu Yun JangSee-Hyoung Park

Published in: Human & experimental toxicology (2022)

Taken together, our results demonstrated that remdesivir has an anti-carcinogenic effect on SKOV3 cells vis up-regulation of reactive oxygen species, which suggests that remdesivir could be a promising reagent for treatment of ovarian cancer.

Keyphrases

reactive oxygen species
induced apoptosis
endothelial cells
cell cycle arrest
induced pluripotent stem cells
oxidative stress
pluripotent stem cells
signaling pathway
smoking cessation