AMIGO2 is involved in the spread of peritoneal metastasis in serous ovarian cancer via promoting adhesion to the peritoneal mesothelial cells.

Yuki IidaMitsuhiko OsakiShinya SatoRuna IzutsuHeeKyung SeongHiroaki KomatsuFuminori TaniguchiFutoshi Okada

Published in: International journal of clinical oncology (2024)

These results suggest that high AMIGO2 expression in serous ovarian carcinoma cells contributes to a poor prognosis by promoting peritoneal metastasis through enhanced cell adhesion to mesothelial cells.

Keyphrases

poor prognosis
induced apoptosis
long non coding rna
cell adhesion
cell cycle arrest
high grade
signaling pathway
cell death
cystic fibrosis
binding protein
pi k akt
high glucose
endothelial cells
pseudomonas aeruginosa
cell migration