Protocol for a Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose FLuoride toothpaste in preventing and treating dEntal Caries in high-risk older adulTs (reflect trial).
Martin TickleD J N RickettsA DuncanL O'MalleyP M DonaldsonJ E ClarksonM BlackD BoyersM DonaldsonR FloateM M ForrestA FraserA M GlennyB GoulaoA McDonaldC R RamsayC RossT WalshH V WorthingtonL YoungD L BonettiJ GouickF E MitchellL E MacphersonY L LinI A PrettyS BirchPublished in: BMC oral health (2019)
ISRCTN: 2017-002402-13 registered 02/06/2017, first participant recruited 03/05/2018. Ethics Reference No: 17/NE/0329/233335. Funding Body: Health Technology Assessment funding stream of National Institute for Health Research. Funder number: HTA project 16/23/01. Trial Sponsor: Manchester University NHS Foundation Trust, Oxford Road, Manchester, M13 9WL. The Trial was prospectively registered.