Compression and tension variably alter Osteoprotegerin expression via miR-3198 in periodontal ligament cells.

Hiroyuki KanzakiSatoshi WadaYuuki YamaguchiYuta KatsumataKanako ItohiyaSari FukayaYutaka MiyamotoTsuyoshi NarimiyaKoji NodaYoshiki Nakamura

Published in: BMC molecular and cell biology (2019)

We conclude that miR-3198 is upregulated by compression and is downregulated by tension, suggesting that miR-3198 downregulates OPG expression in response to mechanical stress.

Keyphrases

long non coding rna
poor prognosis
cell proliferation
long noncoding rna
binding protein
cell cycle arrest
cell death
oxidative stress
stress induced
toll like receptor
heat stress